Moisture Vapor Transmission Rate

PCL can perform a 7, 28, or 35-day test to support packaging system classification or define an MVTR. Different climatic conditioning profiles, durations, and calculations apply based on the USP requirement.

Packaging systems needed for testing include:

  • Control Units: Packaging system without desiccant
  • Sample Units: Packaging system with desiccant

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Industry Application

Moisture vapor transmission rate (MVTR) is a measure of the passage of water vapor through a substrate. Pharmaceuticals require a high level of moisture control to ensure their integrity and shelf life. One of the characteristics of protective packaging systems is to keep moisture from their contents. MVTR helps to ensure the correct level of barrier is applied to the product. The lower the MVTR, the higher the moisture barrier of the system.

MVTR can be performed when the efficacy of the packaging system is challenged:

  • New packaging is introduced
  • Changes in barrier materials occur
  • Changes in manufacturing processes occur